GABA is important for: 

  • Sleep
  • Calm and relaxation
  • Mood
  • Regulating excitability

Serotonin also plays important roles in: 

  • Mental and emotional health (including mood and anxiousness)
  • Aggression
  • Learning
  • Stress response
  • Appetite and cravings
  • Pain perception
  • Libido
  • GI motility
  • Thermoregulation
  • Menstrual health
  • Sleep
  • Calm and relaxation  

Muscle control and coordination Glycine is important in: 

  • Pain perception
  • Detoxification
  • Connective tissue health
  • Sleep



How It Works

Prolent™ helps support inhibitory neurotransmission. This formula contains glycine, ingredients for serotonin synthesis, and ingredients to support GABA release and/or function.

Balance between inhibitory and excitatory neurotransmitters is vital to health and well-being. Inhibitory neurotransmitters such as serotonin, GABA and glycine control excitatory signals in the nervous system. That is why supporting inhibitory neurotransmitters often results in an overall calming and relaxing effect.  

Prolent includes ingredients that support the action of inhibitory neurotransmitters. 5-HTP and vitamin B6 support serotonin synthesis. Theanine, as Suntheanine®, supports both the release of GABA and its function. The combination of these ingredients along with glycine allows Prolent™ to offer comprehensive support for inhibitory neurotransmission.

The NeuroSupport Blend™ (NSB) enhances absorption. Improved absorption allows for smaller doses and fewer capsules. 

Prolent helps prevent over-excitation when catecholamine support is being used. Prolent may be used in Initial, Restoration and Maintenance phases along the path to patient wellnessIt may be combined with LentraSomniTR, or Tranquilent for added inhibitory support.

Explanation of Ingredients

L-theanine as Suntheanine® (standardized to >99%): Shown to promote relaxation by multiple mechanisms including antagonizing glutamate receptors, increasing the release of GABA, and decreasing norepinephrine levels in the brain.

5-HTP:A naturally occurring amino acid and metabolite of L tryptophan. 5-HTP is the direct precursor in the biosynthesis of serotonin. Use of 5-HTP avoids the rate-limiting conversion of tryptophan to 5-HTP. 

Glycine: Functions as an inhibitory neurotransmitter, primarily in the brainstem and spinal cord.

Vitamin B6 (as pyridoxal-5’-phosphate): Active form of B6. Cofactor in conversion of 5-HTP to serotonin. 

NeuroSupport Blend (NSB):Proprietary mixture composed of Bioperine® and plant-based enzymes clinically proven to maximize nutrient absorption.

Supplement Facts

Serving Size: 1 Capsule
Servings Per Container: 60 Capsules

Prolent™ Formula  295mg  
Vitamin B6 (as pyridoxal-5-phosphate)
L-theanine (as Suntheanine®)
5-hydroxytryptophan (Griffonia simplicifolia) (seed)

NSB™ Proprietary Blend  102.5mg
BioPerine® (Black Pepper Extract) (standardized to 95% piperine)(Piper nigrum) (fruit)

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