Contegra™ is a broad-spectrum support formula for those who complain of anxiousness yet are fatigued due to poor sleep quality.


Inhibitory and excitatory neurotransmitter balance is critical for: 

  • Mental and emotional health 
  • Energy 
  • Calm and relaxation 

Adrenal health is important for: 

  • Energy 
  • Stress response 
  • Resilience 
  • Focus 
  • Weight management 
  • Menopause & andropause 
  • Healthy blood sugar regulation 
  • Mental and emotional health  

Thyroid health plays important roles in: 

  • Weight management
  • Energy
  • Digestion
  • Mood


How It Works

Ingredients support inhibitory and excitatory neurotransmitter production, adrenal and thyroid function, and methylation pathways.* It also supplies cofactor and/or phosphorylated forms of B vitamins critical for proper neurotransmitter function.

Ingredients in Contegra™ support balance within the hypothalamic-pituitary-adrenal-thyroid (HPA-T) axis. Contegra also includes ingredients that support inhibitory activity as well as ingredients for excitatory activity to maintain inhibitory and excitatory balance. Healthy methylation is supported by multiple biologically active ingredients. 

The NeuroSupport Blend™ (NSB) enhances absorption. Improved absorption allows for smaller doses and fewer capsules. 

Contegra is often suggested after inhibitory support (Prolent™Lentra™Tranquilent™) has begun and offers a gentle transition to excitatory support. The dose of ingredients supporting excitatory neurotransmitters is higher in Procite-D™ than in ContegraContegra may be used in the Initial, Restoration or Maintenance phases on the path to patient wellness.

Explanation of Ingredients

L-theanine as Suntheanine® (standardized to >99%) Shown to promote relaxation by multiple mechanisms including antagonizing glutamate receptors, increasing the release of GABA, and decreasing norepinephrine levels in the brain.

N-Acetyl-L-Tyrosine Precursor to L-DOPA, the direct precursor to the catecholamines dopamine, norepinephrine and epinephrine. Acetylated for enhanced bioavailability. 

Siberian Ginseng Extract (standardized to 0.8% eleutherosidesEleutherococcus senticosus, an adaptogen thought to attenuate the effects of stress and fatigue.

Iodine (as potassium iodide) Essential component of T3 and T4 thyroid hormones.

Betaine (TrimethylglycineMethylating agent that supports SAMe production/recycling. SAMe is a co-factor in epinephrine synthesis. Also acts as a source of glycine, an inhibitory amino acid neurotransmitter.

Folate (as (6S)-5-methyltetrahydrofolic acid, glucosamine salt) (Quatrefolic®) Cofactor in methylation reactions essential for synthesis of dopamine, norepinephrine and epinephrine. 

Vitamin B6 (as pyridoxal-5’-phosphate): Active form of B6. Cofactor in conversion of L-DOPA to dopamine. 

Vitamin B12 (as Methylcobalamin) Coenzyme form of Vitamin B12. Methyl donor. 

Pantothenic acid (as pantethineBiologically active form of Vitamin B5; adrenal support nutrient. 

NeuroSupport Blend (NSB) Proprietary mixture composed of Bioperine® and plant-based enzymes clinically proven to maximize nutrient absorption.

Supplement Facts

Serving Size: 1 Capsule
Servings per Container: 60 Capsules

Contegra™ Formula  260.85 mg  
Vitamin B6 (as pyridoxal-5-phosphate)
Folate (as (6S)-5-methyltetrahydrofolic acid, glucosamine salt) (Quatrefolic®)
Vitamin B12 (as methylcobalamin)
Pantothenic Acid (as pantethine)
Iodine (as potassium iodide)
Betaine (Trimethylglycine)
L-theanine (as Suntheanine®)
N-Acetyl L-Tyrosine
Siberian Ginseng Extract (std. to 0.8% eleutherosides) (Eleutherococcus senticosus) (stem)

NSB™ Proprietary Blend  102.5mg
BioPerine® (Black Pepper Extract) (standardized to 95% piperine) (Piper nigrum) (fruit)


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